The nurse stresses the importance of reporting which problem during teriparatide therapy?

• A. Headache.
• B. Bone pain.
• C. Dyspepsia.
• D. Rhinitis.

Answer: (B)

Teriparatide is a bone-building therapy for osteoporosis, but it carries a safety signal that makes new or worsening bone pain particularly important to report. While headaches, dyspepsia, or nasal symptoms may occur with this medication, persistent bone pain can indicate abnormal bone remodeling or a rare but serious risk of osteosarcoma, which has been seen in animal studies and warrants prompt evaluation. Reporting bone pain allows the clinician to assess with imaging and labs, consider stopping therapy if needed, and address any calcium balance issues. This focus on bone-related symptoms helps ensure early detection of serious skeletal adverse events, while the other common side effects are typically less urgent and managed symptomatically.